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Annexin A1 plays a role in regulation of growth arrest induced by high levels of estrogen in MCF 7 breast cancer cells via acting as a tumor suppressor involved in modulation of the proliferative functions of estrogens 81, 82 while decreased its expression was associated with breast cancer development and progression 83 <a href=https://buylasixon.com/>lasix adverse effects</a> The vice versa effect can occur as well, where Progestins can and do increase the affinity sensitivity of the Estrogen receptor for Estrogens
