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<a href=http://stromectol.lol>stromectol bed bugs</a> The Nipbl mouse a model of Cornelia de Lange Syndrome CdLS provides a unique resource for studying how the combinatorial effects of genetic variation cause birth defects, because the sole consequence of Nipbl haploinsufficiency appears to be small quantitative adjustments to the levels of expression of hundreds to a thousand genes 21 23, 25